Systemic Therapy

Systemic Therapies Overview

Systemic Therapies

Individuals who have only partial or short responses to skin-directed therapies, or more advanced stages of disease, may benefit from systemic therapy. Learn more about available systemic therapies.


Extracorporeal photopheresis (ECP) was the first therapy approved by the Food and Drug Administration (FDA) specifically for the treatment of cutaneous T-cell lymphoma. ECP may be an effective treatment for CTCL that has not responded to other types of therapy.

What and when are combination therapies used?

Occasionally skin-directed therapies may be used in combination or with a systemic therapy when one therapy alone isn't fully effective.

Treatment Basics

Living with cutaneous lymphoma and understanding the diversity of the treatment options available can be overwhelming. The good news is that there are many treatment options available today.