A wide variety of treatments exist and learning what type may be appropriate for you can be challenging. In this video series, Dr. Rook presents an overview and explanation of treatments and how treatment plans are determined.
Dr. Rook provides an explanation of how cutaneous lymphoma affects the skin and how that determines the type of treatment that is appropriate. Treatments discussed in this video are appropriate for individuals who have limited patches and/or plaques on their skin.
- Potent Topical Steroids
- Nitrogen Mustard
- Narrow band UVB (ultraviolet light therapy)
- PUVA (Psoralin & UVA)
- Other topicals (Retinoids): Imiquiod cream, Targretin gel and Tazorac (Tazarotene) cream or gel
In this video Dr. Rook looks at systemic therapies that are taken by mouth (orally) or through injection as well as treatments for tumors. Systemic therapies may be used for individuals with more than 10% of their skin affected by patches/plaques. Dr. Rook also discusses when bone marrow (stem cell) transplants may be an appropriate treatment option.
- Interferon alpha
- Bexarotene (Targretin - oral)
- Radiation - Total Skin Electron Beam (TSEB)
- HDAC Inhibitors
- Bone Marrow (stem cell) Transplant
In this final video, Dr. Rook focuses on treatments for erythrderma (redness of the skin) related to Sézary syndrome. Targeted tumor therapy is also explored further as is bone marrow transplants.
- Interfern gamma
- Imiquimod cream
- PUVA with Psoralen
- Total Skin Electron Beam (TSEB) therapy
- Targeted tumor therapy: Campath (Alemtuzumab) and Ontak (Denileukin Diftitox)
- HDAC Inhibitors: Vorinostat and Romidepsin
- Allogeneic (bone) Marrow Transplant
- Brentuximab Vedotin