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What are the typical symptoms of cutaneous lymphoma?


Cutaneous T-cell lymphoma, or CTCL, describes many different disorders with various symptoms.

Mycosis fungoides is the most common form of CTCL, and it does not look the same for all patients. This form of CTCL may present itself as patches, plaques or tumors.

Mycosis fungoides typically presents with flat, red, scaly patches that are often mistaken for eczema, psoriasis or non-specific dermatitis. Plaques are thicker, raised lesions. Tumors are raised bumps, which or may not ulcerate (break down). A common characteristic is itching, although some patients do not experience itching. It is possible to have one or all three types of presentations.

Common Signs & Symptoms of Mycosis Fungoides
Patches Plaques
Itching Skin Ulcers


Sezary syndrome is another common form of CTCL, and is considered an advanced, variant of mycosis fungoides, which distinguishes itself by the presence of malignant lymphocytes in the blood.

Sezary syndrome is characterized by diffusely red , scaly, itchy skin (erythroderma) covering over 80 percent of the body. Other skin changes include thickening (hyperkeratosis) of the palms and soles, fragile nails, hair thinning and thickening of the eyelid margins (ectropion). These skin changes are associated with enlarged lymph nodes and the presence of malignant lymphocytes (Sezary cells) circulating in the blood.

Common Signs & Symptoms of Sezary Syndrome
Diffuse Scaling Skin (Erythroderma) Thickening of Palms and Soles (Hyperkeratosis)
Hair Thinning Eyelid Margin Thickening (Ectropion)
Itching Enlarged Lymph Nodes
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