Skin-directed therapies are recommended alone or in combination for treating mycosis fungoides and other early-stage CTCLs. 

For patients with large areas of skin involvement or lymphoma that has spread beyond the skin or has relapsed, systemic therapies that can move through the bloodstream and extend throughout the entire body to reach cancer cells wherever they are located, such as oral retinoids, interferon, or extracorporeal photopheresis, might be used early on in combination with skin-directed treatments,^6,7 depending on the individual patient’s clinical circumstances.  

^aThis list should not be considered exhaustive. Patients and physicians may decide on other combinations that are appropriate for their particular situation. 

Link to References used on page.