Treatment
Treatment Options
Therapeutic Treatment Options for Cutaneous T-Cell Lymphoma
This information attempts to provide patients and their family members with current information on the available treatments for cutaneous lymphomas. This information is not meant to be all inclusive, but rather a launching point for further inquiry. This material should not substitute for thoughtful dialogue between patient, family and an experienced cutaneous lymphoma specialist.
Following is a listing of Skin-Directed and Systemic Therapies:
Skin-Directed Therapies:
Topical therapies:
Topical Corticosteroids
Bexarotene (Targretin®) 1% gel
Topical Chemotherapy:
Mechlorethamine (Mustargen®)
Carmustine (BiCNU®)
Phototherapy:
UVB – Broad & Narrow Band and PUVA
Radiation therapy:
Local & Total Skin Electron Beam Conventional Radiation Therapy
Systemic Therapies:
Targeted/ Biological / Immuno- therapies:
Oral Corticosteroids
Bexarotene (Targretin®) Capsules
Photopheresis
Interferons
Denileukin Diftitox (Ontak®)
Alemtuzumab (Campath®)
HDAC inhibitors:
Vorinostat (Zolinza®)
Romidepsin (Istodax®)
Chemotherapies (Single & Multi-Agent)
Methotrexate
Pentostatin & other purine analogues (Fludarabine, 2- deoxychloroadenosine)
Liposomal doxorubicin (Doxil®)
Gemcitabine (Gemzar®)
Cyclophosphamide, oral
Combination chemotherapy (CHOP regimen)
Bone marrow / Stem cell transplantation:
Bone marrow/Stem cell Allogeneic Transplantation
Last updated August 2010
Additional treatments may be available through clinical trials.
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