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Below are current clinical trials listed by the state of the principle investigator. The list may not include every trial that is available. Some clinical trials are multi-center trials and may be available in more than the one state of the listed principle investigator. You should check with your physician to see if the trial is multi-center.

Colorodo: Aurora
Utah: Salt Lake City

COLOROADO: AURORA
Study of Human Monoclonal Antibody to Treat Mycosis Fungoides and Sézary Syndrome

PURPOSE: The purpose of this study is to determine the efficacy of the drug, HuMax-CD4, in patients with mycosis fungoides(MF) and sezary syndrome who are intolerant to or do not respond to treatment with Targretin® and one other standard therapy.

ELIGIBILITY
Ages Eligible for Study: 18 Years and older
Genders Eligible for Study: Both
Accepts Healthy Volunteers: No

Inclusion Criteria:

* A biopsy compatible with the diagnosis of MF and sezary syndrome with a CD4 positive phenotype within 6 months of study entry
* Refractory to or intolerant to at least two prior therapies, one being Targretin® (or combinations hereof).
* Signed informed consent

Exclusion Criteria:

* Prior treatment with combination chemotherapy within four weeks
* Prior treatment with Total Skin Electron Beam (TSEB) therapy within 6 months.
* Prior treatment with Campath (alemtuzumab)
* Prior treatment with more than three regimens of single agent chemotherapy
* Treatment within 4 weeks prior to study with topical Targretin®, skin directed therapies or systemic anticancer therapies.
* Serious intercurrent medical condition
* Acute or chronic infectious disease.
* Patient with a history of intermittent relapsing herpes simplex skin affections on prophylactic treatment with acyclovir and valacyclovir and patients taking dicloxillin for carriage of staphylococcus aureus maybe included.
* Breast feeding women or women with a positive pregnancy test
* Patients of childbearing potential must practice adequate contraception

CONTACT:
Zena Muzyczenko
1-866-887-1291
mf@us.genmab.com
Please refer to this study by its ClinicalTrials.gov identifier: NCT00127881

UTAH: SALT LAKE CITY
If you have previously treated mycosis fungoides, but have not used topical nitrogen mustard within the last 2 years, you may be eligible for this trial

Utah Clinical Trials, LLC is currently is looking for subjects to participate in a research study of a topical investigational drug for patients with mycosis fungoides.

This is a 12-month study.  Study drug and procedures will be made available to you at no cost. 

To qualify you must:
• Be diagnosed with mycosis fungoides stage I – IIA
• Have not been treated with nitrogen mustard in the last two years
• Not be pregnant or nursing
• Not have had radiation therapy within one year of study start
• Be free of other serious illness

CONTACT INFORMATION:
Utah Clinical Trials, LLC
Salt Lake City, UT 84107
Principal Investigator: Christopher Hull, M.D.
PH: 801-268-1610
chull@utahclinicaltrials.com

ClinicalTrials.gov identifier: NCT00168064